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A comprehensive look at the chemical characteristics, molecular mechanics, and structural superiority of premium Dihydroquercetin.
CAS 480-18-2, systematically recognized as (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydrochromen-4-one, is a bioflavonoid structurally related to quercetin. However, the saturation of the C2-C3 double bond in its molecular skeleton renders it significantly more water-soluble and stable. This structural variance dramatically improves its bio-accessibility, making Dihydroquercetin (DHQ) a highly sought-after compound in advanced clinical nutraceutical and skincare formulations.
Acting as an elite free radical scavenger, CAS 480-18-2 demonstrates a significantly lower EC50 value compared to standard ascorbic acid or synthetic antioxidants like BHT. It prevents lipid peroxidation, stabilizes capillary structures, and promotes cellular longevity. By downregulating inflammatory enzymes such as COX-2 and iNOS, it protects mammalian cell lines from oxidative stress, contributing directly to cardiovascular maintenance and anti-aging benefits.
| Analysis Parameters | Standard Specification | Test Methodology |
|---|---|---|
| Chemical Name | Taxifolin / Dihydroquercetin (DHQ) | Structure Identification |
| CAS Registry Number | 480-18-2 | Database Verification |
| Assay (Purity Grade) | ≥ 98.0% (Dry Basis) | HPLC-UV |
| Physical State | Light yellow to white crystalline powder | Visual Inspection |
| Botanical Source | Larix sibirica (Siberian Larch Wood) | DNA Barcoding / Origin Traceability |
| Heavy Metals (Pb, As, Cd, Hg) | ≤ 10.0 ppm (Total) | ICP-MS |
| Residual Solvents | USP/EP Compliant (Ethanol only, ≤ 0.5%) | GC-Headspace |
| Microbiological Profiles | Total Plate Count ≤ 1000 cfu/g, Yeast/Mold ≤ 100 cfu/g | AOAC Standards |
Integrating scale, purity, and optimization to deliver high-quality CAS 480-18-2 to the international market.
Andy Biotech maintains strategic access to raw material corridors. This direct integration of Siberian Larch wood supply ensures a continuous, sustainably harvested feedstock. By managing logistics from raw timber processing to chemical refinement, we eliminate middle-tier markups and guarantee botanical trace integrity.
Our advanced industrial crystallization reactors process large botanical batches. By scaling crystallization kinetics, we reduce solvent waste and energy consumption per unit output. This ecological focus provides bulk buyers with consistent high purity at a competitive price structure.
Equipped with standardized international documentation (CEP, US FDA DMF potential, SDS, and Custom Tariff codes), we streamline shipping through major ports like Shanghai and Qingdao. We offer dynamic air, sea, and express logistics packages to ensure stable global deliveries.
How Andy Biotech navigates global health standards to ensure seamless regulatory approval.
For enterprises in North America and Europe, chemical sourcing is highly regulated. In the United States, Dihydroquercetin must comply with FDA GRAS status indicators when formulated into foods. In Europe, the European Food Safety Authority (EFSA) enforces strict guidelines on Novel Food approvals for specific plant-based flavonoids.
Andy Biotech ensures that all batches of CAS 480-18-2 pass third-party testing for heavy metals, pesticides, and residual solvents. This rigorous quality control ensures that our extracts enter the supply chain ready for formulation.
We support our corporate clients with comprehensive documentation, including detailed GMP self-audit files, full traceability maps, and analytical data from HPLC validation. We provide on-demand batch records to support regulatory submissions in EU, US, and APAC markets.
Our quality control process is designed to prevent batch-to-batch variation, ensuring our clients receive a highly consistent active ingredient.
From stabilizing active cosmetic formulas to developing health supplements, Taxifolin offers versatile functionality.
In skincare formulation, Dihydroquercetin acts as a powerful inhibitor of UV-induced matrix metalloproteinases (MMPs), protecting dermal collagen and elastin structures. It brightens skin by inhibiting tyrosinase, reducing melanin synthesis, and extending the shelf life of oils in cosmetic emulsions.
In dietary supplements, CAS 480-18-2 supports normal blood viscosity and capillary resistance. It modulates lipid profiles and reduces LDL oxidation, making it a key active ingredient in premium daily heart health supplements.
Due to its high antioxidant activity, Dihydroquercetin serves as a natural food preservative. It protects fats and oils from rancidity and helps preserve color and nutritional value in functional food and beverage formulations.
Andy Biotech is a leading manufacturer and supplier of premium-quality, scientifically-validated plant extracts for the food, beverage, nutraceutical, cosmetic, and pharmaceutical industries. Founded on a commitment to purity, potency, and innovation, we bridge the gap between nature’s potential and your product development goals.
Our core strength lies in our vertically integrated process, which gives us complete control from seed to extract. We partner with a network of certified organic and sustainably managed farms to ensure the integrity of every raw material. Our state-of-the-art extraction facilities employ advanced technologies, including supercritical solvent and water-based methods, to preserve the full spectrum of bioactive compounds without compromising on environmental responsibility.
Strict quality systems and high ingredient purity are at the core of our manufacturing philosophy.
Quality and safety are non-negotiable. Every batch undergoes rigorous testing in our in-house laboratories, equipped with HPLC, GC-MS, and other advanced analytical instruments. We guarantee compliance with stringent international standards, including ISO, NSF, cGMP, and related certifications. Our commitment to transparency means you receive comprehensive Certificates of Analysis (CoA) for every product, ensuring traceability and peace of mind.
It’s one thing to just meet the regulations when providing ingredients, but when an ingredient supplier exceeds those standards and imposes even higher ones in its products that is a sign of a company who cares. Andy Biotech takes extra steps to ensure that our independent third-party laboratory-tested ingredients you want meet our standards as well as your own.
Our extensive portfolio features a wide range of standardized extract, ratio extract, and custom blends tailored to specific formulations. Whether you need Echinacea for immune support, Turmeric with high curcuminoid content, or innovative botanical blends for skincare, our technical team works closely with you to deliver exactly what your product requires. Andy Biotech provide high quality Ginkgo Biloba Extract, Lycopene Tomato Extract, Lutein Marigold Extract, Aloe Vera Gel Freeze Dried powder Aloe Vera Extract and other natural ingredients to food, health and nutraceutical industries.
Answers to key questions regarding specifications, applications, and logistics for CAS 480-18-2.
Premium standardized extracts for nutraceutical, cosmetic, and functional food applications.
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