CAS 20831-76-9, chemically defined as 4-hydroxymethylphenyl-β-D-glucopyranoside and widely known as Gastrodin, is a prominent bioactive glycoside traditionally extracted from the rhizome of Gastrodia elata Blume (Orchidaceae). In modern clinical and nutritional sciences, it stands out as an outstanding neuroprotective and anti-inflammatory agent.
The molecular mechanics of Gastrodin center on its capability to cross the blood-brain barrier (BBB). Inside the central nervous system, it acts to downregulate neuro-inflammation, stabilize mitochondrial membranes, and regulate GABAergic neurotransmission. These mechanisms make it invaluable for formulations targeting migraine relief, cognitive enhancement, anti-fatigue therapies, and overall neurological longevity.
"Gastrodin (CAS 20831-76-9) serves as a therapeutic cornerstone in dietary supplements and functional formulations targeting neuroprotection, stress mitigation, and vascular elasticity."
| Chemical & Technical Specifications | |
|---|---|
| IUPAC Name | (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[4-(hydroxymethyl)phenoxy]oxane-3,4,5-triol |
| Molecular Formula | C13H18O7 |
| Molecular Weight | 286.28 g/mol |
| Assay (HPLC) | ≥98.0% (Pharma & Dietary Supplement Grade) |
| Appearance | White Crystalline Powder |
| Solubility | Highly soluble in water, soluble in methanol and ethanol |
At Andy Biotech, we capitalize on the unique geographical and botanical biodiversity of Shaanxi, China. By establishing vertically integrated cultivation and extraction pipelines, we ensure a seamless bridge between raw botanical material and high-purity, standardized active molecules.
Our raw materials are harvested from certified geographical indication (GI) zones in the Qinling Mountains. Through optimized cultivation protocols, we manage soil quality, irrigation, and harvesting periods to maximize natural Gastrodin content prior to chemical processing. This control keeps our production yields highly predictable and insulated from market price volatility.
Our facilities utilize low-temperature vacuum crystallization and preparative chromatography to isolate CAS 20831-76-9 without thermal degradation. Free from residual chlorinated solvents, our end product features clean dissolution, leaving zero residue when introduced into water-soluble health drinks or parenteral solutions.
For international buyers, chemical purity is only half of the equation; regulatory compliance and local warehouse accessibility represent the other half. Andy Biotech addresses these concerns through a comprehensive regulatory dossier approach.
Andy Biotech: Your Trusted Partner in Plant Extract Solutions
Andy Biotech is a leading manufacturer and supplier of premium-quality, scientifically-validated plant extracts for the food, beverage, nutraceutical, cosmetic, and pharmaceutical industries. Founded on a commitment to purity, potency, and innovation, we bridge the gap between nature’s potential and your product development goals.
Our core strength lies in our vertically integrated process, which gives us complete control from seed to extract. We partner with a network of certified organic and sustainably managed farms to ensure the integrity of every raw material. Our state-of-the-art extraction facilities employ advanced technologies, including supercritical solvent and water-based methods, to preserve the full spectrum of bioactive compounds without compromising on environmental responsibility.
Quality and safety are non-negotiable. Every batch undergoes rigorous testing in our in-house laboratories, equipped with HPLC, GC-MS, and other advanced analytical instruments. We guarantee compliance with stringent international standards, including ISO, NSF, cGMP, and related certifications. Our commitment to transparency means you receive comprehensive Certificates of Analysis (CoA) for every product, ensuring traceability and peace of mind.
It’s one thing to just meet the regulations when providing ingredients, but when an ingredient supplier exceeds those standards and imposes even higher ones in its products that is a sign of a company who cares. Andy Biotech takes extra steps to ensure that our independent third-party laboratory-tested ingredients you want meet our standards as well as your own.
Our extensive portfolio features a wide range of standardized extract, ratio extract, and custom blends tailored to specific formulations. Whether you need Echinacea for immune support, Turmeric with high curcuminoid content, or innovative botanical blends for skincare, our technical team works closely with you to deliver exactly what your product requires. Andy Biotech provide high quality Ginkgo Biloba Extract, Lycopene Tomato Extract, Lutein Marigold Extract, Aloe Vera Gel Freeze Dried powder Aloe Vera Extract and other natural ingredients to food, health and nutraceutical industries.
Andy was born in a small village close to Hanjiang River in Hanzhong Shaanxi province, China. Thirty years ago, when she was still a little child, she caught a cold, but the medical services were not available unless the family crossed over high mountains to find a hospital. Thus, Andy's grandfather first used Echinacea leaves soaked in water for her treatment, then he dug Echinacea root and shredded into pulp and squeezed the liquid for Andy to drink one spoon every two hours. Andy recovered after this treatment.
As a child, Andy watched his grandfather harness the healing power of plants in his humble garden. His ancient herbal remedies were not just treatments; they were magic. That early wonder blossomed into a profound passion for plant extracts and a deep respect for nature’s wisdom. From that time on, little Andy swore that he would help to spread all herbs all over the world to give benefit to more people.
This personal journey is the heart of Andy Biotech. It’s why Andy Biotech are dedicated to researching and delivering the purest, most effective botanical solutions for modern wellness. Andy’s lifelong vow is to honor that tradition by innovating for a healthier future, empowering lives through the timeless power of plants.
With the global rise in stressful lifestyles and aging populations, functional formulas targeting mental clarity and stress mitigation have spiked. Gastrodin’s capacity to support microcirculation within brain tissue and maintain balanced neurotransmitters has positioned it as a premium option in modern nootropic stacks.
The pharmaceutical sector is actively seeking clean-label botanical ingredients that can augment conventional pain relievers. By helping to relieve nerve tension and vascular spasms, CAS 20831-76-9 serves as an excellent natural synergistic compound for migraine management systems.
In cardiovascular health, Gastrodin has been researched for its ability to lower vascular resistance and improve tissue perfusion. Dietary supplement manufacturers incorporate it into longevity and cardiovascular-support products to target arterial elasticity and age-related vascular changes.
In advanced cosmetics, environmental factors often trigger skin sensitivity and sub-clinical inflammation. Gastrodin's neuro-calming and anti-oxidative profile makes it a compelling addition to topical formulas designed to soothe redness and restore the skin barrier.
Our Gastrodin (CAS 20831-76-9) is primarily derived from carefully managed agricultural populations of Gastrodia elata Blume. We can also provide high-purity synthesized or bio-fermented grades depending on client requests and target market specifications.
We employ a water-and-ethanol extraction process. Post-extraction, the product goes through a series of vacuum-evaporation and multi-stage purification steps. Final residues are checked using Gas Chromatography (GC-MS) to confirm compliance with USP, EP, and local food standards.
Every batch shipped is accompanied by a full Certificate of Analysis (CoA), non-irradiated certification, allergen statement, non-GMO declaration, and a heavy metals sheet verified by our ISO-compliant laboratory.
For stock items, we dispatch within 3–5 working days from our factory. For large customized contract manufacturing runs, lead times average between 14 and 21 days, including testing protocols prior to shipping.
Gastrodin is a hygroscopic glycoside. It should be stored in tightly sealed, double-lined food-grade polyethylene bags inside fiber drums, away from light, moisture, and high temperatures. Under these conditions, the shelf life is guaranteed for 24 months.
Yes. We can customize the physical properties of our Gastrodin powder. Our standard powder is 80 mesh, but we can offer finer milling up to 120 mesh or granulate it for directly compressible (DC) tableting setups.
Our production facilities operate under strict compliance with leading international manufacturing frameworks.
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