High-purity botanical raw materials meticulously engineered for food, cosmetic, pharmaceutical, and nutritional supplement manufacturers globally.
Neohesperidin (CAS No. 13241-33-3) is a naturally occurring flavanone glycoside abundant in citrus species, particularly extracted from the young, immature green fruits of *Citrus aurantium L.* (commonly known as bitter orange). Architecturally classified as a citrus flavonoid, neohesperidin functions as an intermediate raw compound for the synthesis of Neohesperidin Dihydrochalcone (NHDC), a high-intensity sweetener and flavor modifier utilized extensively across multi-sector processing industries.
From a biological perspective, Neohesperidin features remarkable antioxidant properties, free radical scavenging capability, and anti-inflammatory attributes. Research indicates its potential in cardiovascular wellness and metabolic management by aiding lipid regulation and bolstering glucose tolerance profiles. By applying advanced isolation techniques, we produce Neohesperidin at varying concentration metrics—typically ranging from 90% to 98% purity (assessed via High-Performance Liquid Chromatography - HPLC)—ensuring targeted therapeutic or organoleptic performance for custom brand formulations.
Our industrial extraction system produces highly standardized crystalline powder with excellent purity profiles. Standard specifications display an off-white to yellowish powder form, high solubility in hot water and organic solvents, and stringent limits on heavy metals (Pb < 2.0ppm, As < 1.0ppm) and pesticide residues, complying directly with current EP, USP, and Chinese Pharmacopoeia (ChP) requirements.
Why sourcing Neohesperidin and citrus derivatives from a primary Chinese manufacturer delivers unparalleled technical and pricing advantages.
Southern and Central China (including Shaanxi, Hunan, and Sichuan provinces) contain the largest cultivated belts of Citrus aurantium. Localized sourcing guarantees a stable, year-round botanical supply, protecting buyers from price volatility.
Our extraction centers employ multi-stage countercurrent extraction systems, continuous chromatographic separation columns, and spray drying systems. This automation maximizes active compound yields while lowering batch energy costs.
From seed cultivation to final milling and packaging, our vertically integrated plant operations track batch genealogy, allowing trace-back of agricultural parameters, solvent profiles, and logistics records.
Navigating the complex regulatory requirements of international food, feed, and pharmaceutical industries requires an experienced manufacturing partner. We provide complete administrative and laboratory support to ensure smooth integration into global target markets.
Our Neohesperidin and derivative compounds (such as NHDC) comply with major global regulatory standards. In the European Union, NHDC is registered as a food additive (E959) and is included in the European Feed Additive Register. In the United States, FEMA has designated NHDC as GRAS (Generally Recognized As Safe) under FEMA number 3811, making it suitable for food, beverage, and personal care formulations.
To support global supply chains, we provide comprehensive documentation packs, including EU REACH compliance certifications, TSE/BSE-free certificates, Non-GMO verification, Allergen declarations, and detailed heavy metal testing reports. Our local warehouse locations and distribution partners in Europe and North America guarantee prompt customs clearing, shortened transit times, and local customer service support.
Andy Biotech: Your Trusted Partner in Plant Extract Solutions
Andy Biotech is a leading manufacturer and supplier of premium-quality, scientifically-validated plant extracts for the food, beverage, nutraceutical, cosmetic, and pharmaceutical industries. Founded on a commitment to purity, potency, and innovation, we bridge the gap between nature’s potential and your product development goals.
Our core strength lies in our vertically integrated process, which gives us complete control from seed to extract. We partner with a network of certified organic and sustainably managed farms to ensure the integrity of every raw material. Our state-of-the-art extraction facilities employ advanced technologies, including supercritical solvent and water-based methods, to preserve the full spectrum of bioactive compounds without compromising on environmental responsibility.
We go beyond compliance to deliver high-quality botanical active ingredients that meet strict global standards.
Quality and safety are non-negotiable. Every batch undergoes rigorous testing in our in-house laboratories, equipped with HPLC, GC-MS, and other advanced analytical instruments. We guarantee compliance with stringent international standards, including ISO, NSF, cGMP, and related certifications. Our commitment to transparency means you receive comprehensive Certificates of Analysis (CoA) for every product, ensuring traceability and peace of mind.
It’s one thing to just meet the regulations when providing ingredients, but when an ingredient supplier exceeds those standards and imposes even higher ones in its products, that is a sign of a company who cares. Andy Biotech takes extra steps to ensure that our independent third-party laboratory-tested ingredients you want meet our standards as well as your own.
Our extensive portfolio features a wide range of standardized extract, ratio extract, and custom blends tailored to specific formulations. Whether you need Echinacea for immune support, Turmeric with high curcuminoid content, or innovative botanical blends for skincare, our technical team works closely with you to deliver exactly what your product requires. Andy Biotech provides high quality Ginkgo Biloba Extract, Lycopene Tomato Extract, Lutein Marigold Extract, Aloe Vera Gel Freeze Dried powder, Aloe Vera Extract, and other natural ingredients to food, health, and nutraceutical industries.
The global natural food ingredients market is undergoing a significant transformation, driven by changing consumer preferences. With rising health awareness, food and beverage manufacturers are seeking clean-label, plant-based sugar alternatives. This shift has elevated demand for compounds like Neohesperidin and NHDC, which serve as clean-label sweetening agents, bitterness blockers, and flavor enhancers.
Additionally, modern animal nutrition utilizes flavor modifiers to improve feed palatability. NHDC, derived from citrus-based Neohesperidin, is highly stable under heat processing and acidic conditions, making it an excellent taste-enhancement additive for animal feed formulations. In the pharmaceutical sector, these ingredients help mask bitter active pharmaceutical ingredients (APIs) in pediatric syrups and chewable tablets, supporting patient compliance.
Unlocking the performance potential of citrus flavonoids across diverse commercial applications.
Applying Neohesperidin derivatives (NHDC) at trace levels (1-5 ppm) helps mask the bitter aftertaste of stevia and monk fruit, enhancing mouthfeel and providing a well-rounded sweetness profile in carbonated soft drinks, functional juices, and protein waters.
Many active ingredients, herbal extracts, and mineral complexes have strong bitter profiles. Sourcing pharmaceutical-grade Neohesperidin enables product formulators to mask off-notes in suspensions, effervescent granules, and chewable tablets without increasing caloric values.
Young farm animals, particularly piglets, are sensitive to taste variations in feed. Incorporating citrus-derived flavor modifiers enhances aroma and taste, supporting consistent feed intake and growth rates during weaning transitions.
Due to its polyphenol structure, Neohesperidin acts as a topical antioxidant, protecting skin structures from UV-induced free radical damage and soothing inflammatory reactions in sensitive skin formulations.
Andy was born in a small village close to Hanjiang River in Hanzhong Shaanxi province, China. Thirty years ago, when she was still a little child, she caught a cold, but the medical services were not available unless the family crossed over high mountains to find a hospital. Thus, Andy's grandfather first used Echinacea leaves soaked in water for her treatment, then he dug Echinacea root and shredded into pulp and squeezed the liquid for Andy to drink one spoon every two hours. Andy recovered after this treatment.
As a child, Andy watched his grandfather harness the healing power of plants in his humble garden. His ancient herbal remedies were not just treatments; they were magic. That early wonder blossomed into a profound passion for plant extracts and a deep respect for nature’s wisdom. From that time on, little Andy swore that he would help to spread all herbs all over the world to give benefit to more people.
This personal journey is the heart of Andy Biotech. It’s why Andy Biotech is dedicated to researching and delivering the purest, most effective botanical solutions for modern wellness. Andy’s lifelong vow is to honor that tradition by innovating for a healthier future, empowering lives through the timeless power of plants.
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Premium botanical extracts manufactured with high purity for health food, beverage, and cosmetic applications.
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