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An in-depth chemical profile, standard structures, and application metrics for commercial formulators.
CAS 3681-99-0 represents the chemical identifier for Mogroside V, the primary bioactive compound and intense natural sweetening agent extracted from the fruit of Siraitia grosvenorii (commonly known as Monk Fruit or Luo Han Guo). Renowned for its outstanding thermo-stability, water-solubility, and non-glycemic characteristics, Mogroside V has established itself as a foundational ingredient in modern sugar-reduction and clean-label formulation strategies.
Chemically, Mogroside V is a triterpene glycoside. It consists of mogrol, a cucurbitane derivative, bound to five glucose molecules. This unique molecular architecture is responsible for its intense sweetness, which ranges from 250 to 300 times sweeter than sucrose, without any bitter, metallic, or chemical aftertaste common to artificial alternatives. Because the human body processes mogrosides differently than conventional sugars, CAS 3681-99-0 provides zero calories and does not spike blood glucose levels, making it highly valuable for diabetic and ketogenic diets.
As a global B2B supplier, Andy Biotech offers standardizations of CAS 3681-99-0 ranging from 20% to 65% HPLC, ensuring our international partners receive customizable sweetness intensities and functional characteristics tailored to their exact formulation processes.
| Parameters | Specifications (Premium Grade) |
|---|---|
| Chemical Name | Mogroside V |
| CAS Number | 3681-99-0 |
| Molecular Formula | C60H102O29 |
| Appearance | Light yellow to off-white fine powder |
| Assay (HPLC) | ≥ 50% Mogroside V (Customizable from 20% - 65%) |
| Solubility | 100% Water Soluble |
| Moisture Content | ≤ 5.0% |
| Heavy Metals | ≤ 10 ppm |
Why procurement officers globally look to Chinese manufacturing infrastructure for CAS 3681-99-0 stability.
Our production facilities benefit from direct access to native cultivation zones in Shaanxi and Guangxi. Growing under perfect climatic conditions, the raw materials are rich in active mogrosides, translating directly to yield consistency and cost efficiency.
We implement state-of-the-art chromatographic separation and countercurrent extraction technologies. This preserves the delicate chemical structure of CAS 3681-99-0, minimizing degradations and eliminating potential off-flavors.
Equipped with expansive manufacturing plants and warehouse hubs, we insulate global brands from raw material shocks. From trial batches to full-scale container shipments, we maintain consistent supply lines.
Andy Biotech is a leading manufacturer and supplier of premium-quality, scientifically-validated plant extracts for the food, beverage, nutraceutical, cosmetic, and pharmaceutical industries. Founded on a commitment to purity, potency, and innovation, we bridge the gap between nature’s potential and your product development goals.
Our core strength lies in our vertically integrated process, which gives us complete control from seed to extract. We partner with a network of certified organic and sustainably managed farms to ensure the integrity of every raw material. Our state-of-the-art extraction facilities employ advanced technologies, including supercritical solvent and water-based methods, to preserve the full spectrum of bioactive compounds without compromising on environmental responsibility.
Quality and safety are non-negotiable. Every batch undergoes rigorous testing in our in-house laboratories, equipped with HPLC, GC-MS, and other advanced analytical instruments. We guarantee compliance with stringent international standards, including ISO, NSF, cGMP, and related certifications. Our commitment to transparency means you receive comprehensive Certificates of Analysis (CoA) for every product, ensuring traceability and peace of mind.
It’s one thing to just meet the regulations when providing ingredients, but when an ingredient supplier exceeds those standards and imposes even higher ones in its products that is a sign of a company who cares. Andy Biotech takes extra steps to ensure that our independent third-party laboratory-tested ingredients you want meet our standards as well as your own.
Our extensive portfolio features a wide range of standardized extract, ratio extract, and custom blends tailored to specific formulations. Whether you need Echinacea for immune support, Turmeric with high curcuminoid content, or innovative botanical blends for skincare, our technical team works closely with you to deliver exactly what your product requires. Andy Biotech provide high quality Ginkgo Biloba Extract, Lycopene Tomato Extract, Lutein Marigold Extract, Aloe Vera Gel Freeze Dried powder, Aloe Vera Extract, and other natural ingredients to food, health, and nutraceutical industries.
Integrating Mogroside V CAS 3681-99-0 into high-performance industrial formulations.
Excellent water solubility and exceptional pH stability (retains sweetness and structure down to pH 2.0) make CAS 3681-99-0 ideal for RTD tea, sparkling waters, energy drinks, and dairy-free milk alternatives. It blends seamlessly without precipitation.
Unlike aspartame or other synthetic sweeteners, Mogroside V remains structurally stable at temperatures up to 160°C. This allows industrial baking and confectionery brands to produce zero-sugar biscuits, cakes, and hard candies without structural degradation.
Many botanical supplements, plant proteins, and pharmaceutical syrups carry inherent bitterness. CAS 3681-99-0 functions as a powerful natural taste-masking agent, improving consumer compliance while maintaining a clean label status.
Andy was born in a small village close to Hanjiang River in Hanzhong Shaanxi province, China. Thirty years ago, when she was still a little child, she caught a cold, but the medical services were not available unless the family crossed over high mountains to find a hospital. Thus, Andy's grandfather first used Echinacea leaves soaked in water for her treatment, then he dug Echinacea root and shredded into pulp and squeezed the liquid for Andy to drink one spoon every two hours. Andy recovered after this treatment.
As a child, Andy watched her grandfather harness the healing power of plants in his humble garden. His ancient herbal remedies were not just treatments; they were magic. That early wonder blossomed into a profound passion for plant extracts and a deep respect for nature’s wisdom. From that time on, little Andy swore that she would help to spread all herbs all over the world to give benefit to more people.
This personal journey is the heart of Andy Biotech. It’s why Andy Biotech is dedicated to researching and delivering the purest, most effective botanical solutions for modern wellness. Andy’s lifelong vow is to honor that tradition by innovating for a healthier future, empowering lives through the timeless power of plants.
Understanding the micro-economic shift towards natural sweeteners and clean labels.
Over 50 jurisdictions worldwide now enforce sugar levies on processed goods. Utilizing CAS 3681-99-0 allows global food and beverage corporations to reformulate products to fall below tax thresholds, reducing costs while retaining taste parity.
Consumers actively bypass products containing chemical sweeteners like sucralose, acesulfame potassium, and aspartame. Natural sweeteners like Monk Fruit Mogroside V satisfy consumer desires for natural, plant-based, recognizable ingredients.
Industrial formulators are increasingly turning to synergistic natural systems. Combining CAS 3681-99-0 with erythritol, stevia, or NHDC helps optimize sweetness curves, reducing flavor drop-off and matching the mouthfeel of sucrose.
Crucial industrial data and regulatory compliance questions addressed by our technical growth team.
CAS 3681-99-0 is the unique Chemical Abstracts Service registry number for Mogroside V, a natural triterpene glycoside extract from the fruit of Siraitia grosvenorii (Monk Fruit). It functions as a zero-calorie, high-intensity sweetener.
Yes, Monk Fruit Extract containing Mogroside V is GRAS (Generally Recognized as Safe) certified by the US FDA. In the European Union, it is approved under EFSA guidelines for specified food category additions, and widely accepted in global regions like Japan, Canada, and Australia.
We manufacture and supply standard specifications ranging from 20% to 65% Mogroside V (HPLC). We also provide custom blends with erythritol or stevia to match specific customer requirements.
No. Mogroside V is extremely thermally stable. It is capable of resisting degradation during standard pasteurization, Ultra-High Temperature (UHT) sterilization, and commercial baking cycles without losing its sweetening power.
Through our vertically integrated supply chain, we control agricultural cultivation, harvesting, extraction, and laboratory analysis. Each production batch is assigned a unique batch number, linking directly to its raw material origins and HPLC analytical reports.
We supply both pure 100% Monk Fruit extract powders with no carriers, and custom standardized formulations utilizing food-grade carriers (like maltodextrin) to meet specific flowability and density needs in automated packaging plants.
Our manufacturing systems conform to cGMP, ISO 9001, ISO 22000, Kosher, Halal, and USDA Organic standards. Full documentation and certificates are provided with every wholesale shipment.
Pure high-grade Mogroside V (especially at concentrations above 50%) has a clean taste profile with minimal lingering sweetness. In applications where aftertaste is an issue, our R&D team recommends custom blending with other plant extracts or sugar alcohols.
Under dry, cool storage conditions in the original unopened container, the shelf life of our Mogroside V powder is 24 months from the manufacturing date.
Our standard MOQ for wholesale raw material is 25kg (one full drum). However, we accommodate smaller trial orders (1kg–5kg) for research, development, and formulation test phases.
Our facilities and processes adhere strictly to international manufacturing regulations.
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