China Suppliers Factory Supply Citrus Aurantium Extract 98% Neohesperidin CAS 13241-33-3 for Health Supplements

Neohesperidin is a highly valued citrus flavonoid with significant industrial applications, particularly as a primary ingredient in the production of the super-high-potency sweetener NHDC. Sourced from reputable suppliers in China, Neohesperidin is not only remarkable for its industrial utility but also recognized for its bioactive properties. It boasts potent antioxidant, anti-inflammatory, and vascular-protective effects, making it an exciting area of exploration in health and pharmaceutical research. Our factory is committed to providing high-quality Neohesperidin, catering to the growing demand in various industries

Product Description

Product Specification

Neohesperidin, CAS 13241-33-3 — Technical Data Sheet
Sense Index
Appearance Light yellow to off-white powder
Odor & Taste Characteristic
Physical-chemical Index
Neohesperidin 98% Min
Loss on drying 5% Max
Ash 5% Max
Particle Size 98% pass 80 mesh
Heavy metals 10 ppm Max
Lead 2 ppm Max
Arsenic 2 ppm Max
Mercury 0.1 ppm Max
Cadmium 1 ppm Max
Hygienic Index
Total plate count 1,000 cfu/g Max
Mold & Yeast 100 cfu/g Max
Enterobacteriae 10 cfu/g Max
E. Coli Absent in 10 g
Salmonella Absent in 25 g
Statements: Non-Irradiated, Non-GMO
Shelf Life: 24 months stored in original packaging away from the light and under the optimal temperature 10–25 °C.
Packaging: 1 kg / aluminium foil bag or 25 kg / fiber drum.

Function of Neohesperidin

Neohesperidin, a citrus-derived flavanone glycoside, exerts potent free radical scavenging and anti-inflammatory effects by inhibiting inflammatory factors and modulating stress-related pathways. It protects cardiovascular health by enhancing capillary toughness, improving microcirculation and maintaining normal vascular permeability.

Additionally, it regulates intestinal flora, supports liver function by reducing fat accumulation and hepatocyte damage and serves as a key precursor for NHDC — a high-intensity low-calorie sweetener 1,500–2,000 times sweeter than sucrose.

Its antioxidant and anti-aging properties also make it valuable for skin care, while it aids in balancing blood lipids and alleviating intestinal inflammation.

Neohesperidin, CAS 13241-33-3

Application Area of Neohesperidin

Food Industry
  • Raw material for synthesizing neohesperidin dihydrochalcone (NHDC), a high-intensity sweetener.
  • Used as a flavor enhancer, bitterness masking agent, and preservative in beverages, candy, baked goods and low-sugar foods.
Pharmaceutical & Healthcare
  • Cardiovascular health supplements to improve capillary fragility and microcirculation.
  • Antioxidant and anti-inflammatory ingredients for liver protection and metabolic regulation.
  • Used in oral and gastrointestinal healthcare formulations.
Cosmetics & Skin Care
  • Antioxidant, anti-aging, and soothing components in creams, serums, and lotions.
  • Inhibits melanin production, brightens skin and relieves redness and sensitivity.
Daily Chemical & Oral Care
  • Added in toothpaste, mouthwash and chewing gum to enhance flavor and mask bitterness.
Feed & Animal Nutrition
  • Used as a natural antioxidant and growth promoter to improve animal intestinal health and immunity.

Frequently Asked Questions

QWhat is Neohesperidin (CAS 13241-33-3)?
Neohesperidin is a naturally occurring flavanone glycoside found primarily in citrus fruits such as bitter orange (Citrus aurantium). It is widely used as a bioactive ingredient in food, pharmaceuticals, cosmetics, and animal nutrition due to its strong antioxidant, anti-inflammatory, and cardiovascular-protective properties.
QWhat is the purity specification of your Neohesperidin?
Our Neohesperidin meets a minimum purity of 98%, with loss on drying ≤5%, ash ≤5%, and particle size of 98% passing 80 mesh. Heavy metal content is strictly controlled: total heavy metals ≤10 ppm, lead ≤2 ppm, arsenic ≤2 ppm, mercury ≤0.1 ppm, and cadmium ≤1 ppm.
QWhat is the relationship between Neohesperidin and NHDC?
Neohesperidin is the direct precursor for synthesizing Neohesperidin Dihydrochalcone (NHDC), a high-intensity, low-calorie sweetener that is approximately 1,500–2,000 times sweeter than sucrose. NHDC is widely used in the food and beverage industry as a sugar substitute and flavor modifier.
QHow should Neohesperidin be stored and what is its shelf life?
Neohesperidin should be stored in its original packaging, away from light, at an optimal temperature of 10–25 °C. Under these conditions, the shelf life is 24 months. Avoid exposure to moisture, heat, and direct sunlight to maintain product quality.
QWhat packaging options are available for Neohesperidin?
Neohesperidin is available in two packaging options: 1 kg per aluminium foil bag for laboratory or small-scale use, and 25 kg per fiber drum for bulk industrial orders. Both options are designed to protect the product from moisture and light during storage and transport.
QIs Neohesperidin Non-GMO and non-irradiated?
Yes. Our Neohesperidin is certified Non-GMO and Non-Irradiated. It also meets strict microbiological standards: total plate count ≤1,000 cfu/g, mold & yeast ≤100 cfu/g, and is free from E. Coli and Salmonella, ensuring it is safe for use in food, pharmaceutical, and cosmetic applications.

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