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Shikimic Acid (CAS No. 138-59-0), chemical formula C7H10O5, represents one of the most critical hydroaromatic intermediates synthesized via the shikimate pathway in plants and micro-organisms. Historically valued as the primary starting precursor for Oseltamivir Phosphate (Tamiflu), a critical global antiviral medication, CAS No. 138-59-0 has rapidly transitioned into a multifunction active ingredient across cosmetic science and industrial biotechnology.
From a chemical structure perspective, Shikimic Acid is a cyclohexenecarboxylic acid, featuring three chiral hydroxyl groups that act as highly active reaction sites. This stereochemical complexity makes traditional synthetic chemistry highly inefficient, elevating natural extraction and biosynthesis to the forefront of modern chemical manufacturing.
| Parameter | Technical Specification |
|---|---|
| IUPAC Name | (3R,4S,5R)-3,4,5-trihydroxycyclohex-1-ene-1-carboxylic acid |
| Molecular Weight | 174.15 g/mol |
| Melting Point | 185 °C to 187 °C (Highly Crystalline White Powder) |
| Solubility | Highly soluble in water (180 g/L at 20 °C); insoluble in ether and chloroform. |
| Optical Rotation | -180° (c=1, H2O) |
As a leading CAS No. 138-59-0 manufacturer and factory, Andy Biotech leverages state-of-the-art multi-stage extraction and isolation technologies to provide high-purity Shikimic Acid (up to 99% by HPLC). This ensures that batch-to-batch consistency matches the rigorous specifications demanded by pharmaceutical intermediates and high-end personal care formulations.
Shikimic Acid is no longer just a pharmaceutical precursor; it has transitioned into a highly sought-after functional active ingredient globally.
Crucial starting block for Oseltamivir synthesis. Global supply security demands reliable bulk supply pipelines to hedge against seasonal epidemic waves and regional shortages.
Shikimic acid acts as a natural, non-irritating alternative to Salicylic Acid (BHA) and Glycolic Acid (AHA). It offers excellent exfoliating, anti-acne, and antimicrobial activity at lower concentrations.
Exhibits significant cellular antioxidant and anti-thrombotic properties. Formulators integrate CAS No. 138-59-0 into cardiovascular and immune support supplement blends.
In response to supply chain disruptions and the fluctuating availability of raw materials like Star Anise (Illicium verum), modern manufacturers must establish resilient sourcing architectures. Andy Biotech addresses these challenges by developing a dual-track raw material strategy. By combining high-yield botanical extraction with biosynthetic fermentation techniques, we shield global procurement managers from extreme market fluctuations.
Our global shipping networks and strategically positioned distribution centers enable us to guarantee consistent lead times. This reduces the need for expensive warehousing and excessive safety stock for key pharmaceutical and cosmetic manufacturers worldwide.
Exploring the production pathways of CAS No. 138-59-0: Botanical Extraction versus Biosynthetic Fermentation.
Traditionally, Shikimic Acid is extracted from the seeds and pods of Star Anise (Illicium verum Hook. f.). The process involves extraction with hot water or ethanol, followed by separation through macroporous adsorption resins and crystallization.
To ensure supply chain stability, Andy Biotech has invested in biosynthetic engineering. By utilizing genetically modified strains of Escherichia coli or Saccharomyces cerevisiae, we transform simple carbon sources (glucose) into highly concentrated Shikimic Acid.
The manufacturing future of CAS No. 138-59-0 relies on hybrid business models. By combining agricultural extraction with industrial fermentation, factories can optimize costs and protect against supply chain shocks, ensuring a stable supply of this crucial pharmaceutical building block.
Andy Biotech is committed to minimizing chemical waste. Our production lines feature closed-loop solvent recycling systems that recover up to 95% of extraction solvents.
By shifting to enzymatically catalyzed purification processes, we have cut heavy industrial energy usage by 30%, aligning our operations with corporate ESG goals and sustainable purchasing practices.
Did you know? Shikimic Acid serves as a key biosynthetic intermediate in plants for producing the aromatic amino acids L-phenylalanine, L-tyrosine, and L-tryptophan.
Andy Biotech: Your Trusted Partner in Plant Extract Solutions
Andy Biotech is a leading manufacturer and supplier of premium-quality, scientifically-validated plant extracts for the food, beverage, nutraceutical, cosmetic, and pharmaceutical industries. Founded on a commitment to purity, potency, and innovation, we bridge the gap between nature’s potential and your product development goals.
Our core strength lies in our vertically integrated process, which gives us complete control from seed to extract. We partner with a network of certified organic and sustainably managed farms to ensure the integrity of every raw material. Our state-of-the-art extraction facilities employ advanced technologies, including supercritical solvent and water-based methods, to preserve the full spectrum of bioactive compounds without compromising on environmental responsibility.
Quality and safety are non-negotiable. Every batch undergoes rigorous testing in our in-house laboratories, equipped with HPLC, GC-MS, and other advanced analytical instruments. We guarantee compliance with stringent international standards, including ISO, NSF, cGMP, and related certifications. Our commitment to transparency means you receive comprehensive Certificates of Analysis (CoA) for every product, ensuring traceability and peace of mind.
It’s one thing to just meet the regulations when providing ingredients, but when an ingredient supplier exceeds those standards and imposes even higher ones in its products, that is a sign of a company who cares. Andy Biotech takes extra steps to ensure that our independent third-party laboratory-tested ingredients you want meet our standards as well as your own.
Our extensive portfolio features a wide range of standardized extract, ratio extract, and custom blends tailored to specific formulations. Whether you need Echinacea for immune support, Turmeric with high curcuminoid content, or innovative botanical blends for skincare, our technical team works closely with you to deliver exactly what your product requires. Andy Biotech provide high quality Ginkgo Biloba Extract, Lycopene Tomato Extract, Lutein Marigold Extract, Aloe Vera Gel Freeze Dried powder Aloe Vera Extract and other natural ingredients to food, health and nutraceutical industries.
Andy was born in a small village close to Hanjiang River in Hanzhong Shaanxi province, China. Thirty years ago, when she was still a little child, she caught a cold, but the medical services were not available unless the family crossed over high mountains to find a hospital. Thus, Andy's grandfather first used Echinacea leaves soaked in water for her treatment, then he dug Echinacea root and shredded into pulp and squeezed the liquid for Andy to drink one spoon every two hours. Andy recovered after this treatment.
As a child, Andy watched his grandfather harness the healing power of plants in his humble garden. His ancient herbal remedies were not just treatments; they were magic. That early wonder blossomed into a profound passion for plant extracts and a deep respect for nature’s wisdom. From that time on, little Andy swore that he would help to spread all herbs all over the world to give benefit to more people.
This personal journey is the heart of Andy Biotech. It’s why Andy Biotech are dedicated to researching and delivering the purest, most effective botanical solutions for modern wellness. Andy’s lifelong vow is to honor that tradition by innovating for a healthier future, empowering lives through the timeless power of plants.
Andy Biotech maintains global standards of excellence, backed by rigorous verification audits from international quality institutions.
Navigating complex global compliance is essential when importing chemical compounds and active pharmaceutical intermediates.
Different markets have distinct requirements for compounds like CAS No. 138-59-0. Andy Biotech handles the heavy lifting of compliance by maintaining up-to-date documentation and active dossiers for the world's major regulatory markets:
Our quality management systems track every batch back to its raw material source. From harvesting records to chromatographic testing in our labs, we document every critical process step. This level of traceability helps our clients pass audits by global regulators and major multi-national consumer brands.
Answers to common technical, manufacturing, and logistics questions about CAS No. 138-59-0.
Broader chemical and biological active portfolios manufactured at our GMP-certified plant extract facilities.
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