Direct factory supply of bio-active extracts with stringent purity certifications for food, nutraceutical, and pharmaceutical industries.
Icariin, a prenylated flavonol glycoside extracted primarily from species of the Epimedium genus (commonly known as Horny Goat Weed), has transitioned from traditional pharmacopeias to a cornerstone of modern bio-active manufacturing. Functioning as a natural PDE5 inhibitor, phytoestrogen, and osteogenic agent, Icariin (CAS No: 489-32-7) is experiencing a surge in demand across global medical research, nutraceutical development, and functional food sectors.
High-purity Icariin (up to 98% by HPLC) is heavily researched for cardiovascular protection, osteoblast differentiation support, and neuroprotective qualities, signaling a strong pharmaceutical demand pipeline.
Common commercial formulations require strict standards ranging from 10%, 20%, to 50% Icariin content, driving dietary supplement companies to seek reliable direct-factory extraction partners.
The compound's documented role in enhancing nitric oxide production and cellular metabolism makes it a priority ingredient in performance, energy, and hormonal optimization formulations globally.
Maximum Purity (HPLC)
Annual Production Capacity
Certified Manufacturing
Traceable Supply Chain
China represents over 90% of the global Epimedium raw material supply and refined extraction capacity. The unique geographical advantages, paired with deep industrial scaling, position Chinese factories at the apex of the global supply chain.
The Qinling Mountains in Shaanxi province and the surrounding mountainous terrains of Gansu and Sichuan host the native wild habitats of key Epimedium species such as Epimedium brevicornum Maxim and Epimedium sagittatum. Sourcing facilities located in Shaanxi enjoy direct access to wild-harvested and sustainably cultivated raw materials, dramatically reducing transportation costs and preserving the bio-activity of the leaves prior to processing.
Chinese extraction facilities have integrated continuous countercurrent extraction, macroporous resin chromatography, and molecular distillation. This allows for high-yield runs, making high-purity batching commercially viable. Compared to Western processors, Chinese factories offer an unparalleled cost-to-potency ratio while maintaining matching standards of purity and heavy metal control.
Andy Biotech is a leading manufacturer and supplier of premium-quality, scientifically-validated plant extracts for the food, beverage, nutraceutical, cosmetic, and pharmaceutical industries. Founded on a commitment to purity, potency, and innovation, we bridge the gap between nature’s potential and your product development goals.
Our core strength lies in our vertically integrated process, which gives us complete control from seed to extract. We partner with a network of certified organic and sustainably managed farms to ensure the integrity of every raw material. Our state-of-the-art extraction facilities employ advanced technologies, including supercritical solvent and water-based methods, to preserve the full spectrum of bioactive compounds without compromising on environmental responsibility.
Depending on target markets and regulatory structures (FDA, EFSA, NMPA), Icariin finds distinct integration points into consumer-facing formulations:
Incorporated into dry-mix pre-workouts and hormonal support complexes, typically standardized to 10%–20% Icariin, combined with L-Arginine, Maca, and Zinc.
Utilized in bone density support formulations targeting postmenopausal demographics, leveraging Icariin's proven estrogenic mimicry and osteogenic signaling.
Formulated as highly soluble liquid extracts or instant herbal teas, blending Epimedium extract with Ginseng and Reishi to appeal to traditional wellness demographics.
Quality and safety are non-negotiable. Every batch undergoes rigorous testing in our in-house laboratories, equipped with HPLC, GC-MS, and other advanced analytical instruments. We guarantee compliance with stringent international standards, including ISO, NSF, cGMP, and related certifications. Our commitment to transparency means you receive comprehensive Certificates of Analysis (CoA) for every product, ensuring traceability and peace of mind.
It’s one thing to just meet the regulations when providing ingredients, but when an ingredient supplier exceeds those standards and imposes even higher ones in its products that is a sign of a company who cares. Andy Biotech takes extra steps to ensure that our independent third-party laboratory-tested ingredients you want meet our standards as well as your own.
Our extensive portfolio features a wide range of standardized extract, ratio extract, and custom blends tailored to specific formulations. Whether you need Echinacea for immune support, Turmeric with high curcuminoid content, or innovative botanical blends for skincare, our technical team works closely with you to deliver exactly what your product requires. Andy Biotech provide high quality Ginkgo Biloba Extract, Lycopene Tomato Extract, Lutein Marigold Extract, Aloe Vera Gel Freeze Dried powder Aloe Vera Extract and other natural ingredients.
The global phytotherapy market is moving rapidly toward clean-label extraction and specific molecular isolating methods. Key developments shaping the future of Icariin supply chains include:
"Andy was born in a small village close to Hanjiang River in Hanzhong Shaanxi province, China. Thirty years ago, when she was still a little child, she caught a cold, but the medical services were not available unless the family crossed over high mountains to find a hospital. Thus, Andy's grandfather first used Echinacea leaves soaked in water for her treatment, then he dug Echinacea root and shredded into pulp and squeezed the liquid for Andy to drink one spoon every two hours. Andy recovered after this treatment."
As a child, Andy watched his grandfather harness the healing power of plants in his humble garden. His ancient herbal remedies were not just treatments; they were magic. That early wonder blossomed into a profound passion for plant extracts and a deep respect for nature’s wisdom. From that time on, little Andy swore that he would help to spread all herbs all over the world to give benefit to more people.
This personal journey is the heart of Andy Biotech. It’s why Andy Biotech are dedicated to researching and delivering the purest, most effective botanical solutions for modern wellness. Andy’s lifelong vow is to honor that tradition by innovating for a healthier future, empowering lives through the timeless power of plants.
When sourcing Icariin from Chinese manufacturers, corporate procurement divisions must validate key production parameters to ensure regulatory safety, supply consistency, and cost optimization:
Confirm that raw plant processing strictly adheres to USP <467> guidelines. Clean ethanolic extracts prevent regulatory rejection at import customs.
Ensure Lead (Pb) <3.0 ppm, Arsenic (As) <1.0 ppm, Cadmium (Cd) <0.5 ppm, and Mercury (Hg) <0.1 ppm to comply with global food standards.
Request testing protocols that clearly differentiate between Icariin and total flavonoids (Icariins), preventing analytical discrepancies.
Our verified production lines operate under strict global quality standards, validated by national and international regulatory credentials.
"Icariin" refers strictly to the single monomeric compound (C33H40O15) verified by HPLC. "Icariins" (plural) typically refers to the total active flavonoids present in the Epimedium extract, including epimedin A, B, and C. Buyers should clarify this assay target before placing orders.
We primarily use Epimedium brevicornum Maxim and Epimedium sagittatum, sourced from partners in Shaanxi and Sichuan, which yields the most stable and concentrated active icariin compounds.
We supply standardized powders at 10%, 20%, 50%, 60%, and up to 98% HPLC. We also offer customized ratio extracts (e.g., 4:1, 10:1) to fit various functional supplement formulation requirements.
Every production run is tested in-house using ICP-MS for heavy metals. Our extraction methods ensure strict conformity to EC Regulation 1881/2006 for Polycyclic Aromatic Hydrocarbons (PAHs) and pesticide residues.
Standard high-purity Icariin is hydrophobic and has limited water solubility. However, we offer specialized water-dispersible formulations optimized for functional beverage brands.
Standard stock items are dispatched within 3–5 working days. Large contract orders or customized blends typically require 2–3 weeks depending on harvest seasons and raw material profiling.
Yes. We routinely collaborate with independent analytical labs like Eurofins, SGS, or NSF to supply independent testing reports directly to international buyers.
Standard B2B packaging consists of 25kg fiber drums lined with dual-layered food-grade polyethylene bags. Storage in cool, dry areas away from direct sunlight preserves potency for up to 24 months.
Examine our broader range of premium, organic-certified active botanical ingredients below.
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