Direct supply from state-of-the-art Chinese botanical extraction facility. Complete quality standard compliance.
CAS 491-70-3, scientifically known as Luteolin [3',4',5,7-tetrahydroxyflavone], represents one of the most clinically researched and commercially sought-after natural yellow flavonoid compounds in existence today. Typically derived from plants like Sophora japonica, peanut shells, chamomile, and artichoke, Luteolin's rich molecular configuration of hydroxyl groups provides it with unparalleled free-radical scavenging capabilities.
For global nutraceutical, cosmetic, and pharmaceutical industries, CAS 491-70-3 has evolved from a basic bioflavonoid component to a high-value active pharmaceutical ingredient (API) and wellness formulation cornerstone. Its capability to cross the blood-brain barrier under specific delivery systems makes it particularly valuable for neuroprotective formulations, cognitive wellness supplements, and anti-aging cosmetic serums.
The international demand for high-purity Luteolin (purity level ≥ 98% by HPLC) is experiencing an unprecedented CAGR of 8.4% over the current projection window. This demand is driven by the structural pivot of consumer markets toward plant-based longevity protocols and preventive medicine.
Currently, North American and European nutraceutical markets lead imports of wholesale CAS 491-70-3 powder, integrating it heavily into cellular health formulas, mitochondrial supportive supplements, and allergy management solutions. Concurrently, cosmetic conglomerates in Asia-Pacific are utilizing Luteolin's natural tyrosinase-inhibiting properties to engineer high-end clean-label skin brightening and UV-recovery products.
How Andy Biotech employs green extraction technology to achieve superior purity metrics and molecular stability.
Breaking down complex plant cell wall structures using eco-friendly cellulase and pectinase enzymes. This increases the mass transfer rate of Luteolin, optimizing yields by up to 25% without chemical degradation.
Utilizing high-pressure CO2 supplemented by food-grade ethanol as a co-solvent. This method completely eliminates heavy toxic organic solvents (like hexane or chloroform), ensuring clean chemical profiles.
Multi-stage chromatography coupled with controlled crystallization parameters to refine the raw filtrate into a highly refined crystalline structure, securing consistent >98% active assay profiles.
Our optimization laboratory recently achieved a major milestone in demethylation technology. Under specific enzymatic hydrolysis conditions, we convert co-extracted flavonoids (such as rutin and quercetin variants) into high-purity luteolin intermediates. This not only increases the raw botanical utility rate but also significantly reduces the environmental footprint and cost matrix for bulk purchasers seeking stable long-term supply agreements.
Andy Biotech: Your Trusted Partner in Plant Extract Solutions
Andy Biotech is a leading manufacturer and supplier of premium-quality, scientifically-validated plant extracts for the food, beverage, nutraceutical, cosmetic, and pharmaceutical industries. Founded on a commitment to purity, potency, and innovation, we bridge the gap between nature’s potential and your product development goals.
Our core strength lies in our vertically integrated process, which gives us complete control from seed to extract. We partner with a network of certified organic and sustainably managed farms to ensure the integrity of every raw material. Our state-of-the-art extraction facilities employ advanced technologies, including supercritical solvent and water-based methods, to preserve the full spectrum of bioactive compounds without compromising on environmental responsibility.
How downstream innovators across global markets apply CAS 491-70-3 to diverse commercial applications.
Utilized as the central active ingredient in cellular longevity formulas. Luteolin inhibits mast cell activation and microglia-induced neuroinflammation. Often combined with palmitoylethanolamide (PEA) or quercetin for synergistic absorption enhancement.
Formulated into high-potency anti-wrinkle and UV protection cosmetics. By neutralizing reactive oxygen species (ROS) and downregulating matrix metalloproteinases (MMPs), it protects dermal collagen structures from premature breakdown.
Water-soluble complexes of Luteolin (using beta-cyclodextrin carrier technology) are integrated into modern functional energy drinks, recovery teas, and stress-mitigation wellness shots targeting modern urban demographics.
Applied in high-end veterinary feeds and companion animal joint supplements to reduce systemic inflammation. Improves immune system signaling in livestock without utilizing synthetic antibiotics.
Setting the industry benchmark for purity, transparency, and sustainable sourcing.
Operating in Shaanxi province, the geographical heart of China's herbal extraction industry, Andy Biotech commands unique geographical and botanical sourcing advantages. Shaanxi has historically been the focal point of agricultural biotechnology research in China, yielding direct access to raw raw materials (such as high-quality Sophora Japonica crops and agricultural peanut hubs) and optimized infrastructure.
Our facility’s logistical resilience relies on robust raw material storage systems coupled with state-of-the-art intelligent processing pipelines. We maintain a continuous rolling raw plant inventory sufficient to weather sudden market surges or seasonal agricultural challenges. By partnering with leading global maritime and air freight carriers, we guarantee prompt door-to-door delivery with transparent cold-chain security systems when required.
Furthermore, our energy mitigation strategy ensures zero production downtime. Utilizing an integrated cogeneration energy plant within our industrial park, we maintain low energy costs, allowing us to insulate our wholesale buyers from volatile raw material pricing fluctuations. That is why Fortune 500 nutraceutical brands consistently trust Andy Biotech as their stable long-term primary supplier of CAS 491-70-3.
Our processing facility and manufacturing processes conform to globally recognized regulatory benchmarks.
Navigating the regulatory landscape for botanical extracts requires meticulous compliance verification. Andy Biotech ensures that all exports of CAS 491-70-3 comply with safety standards including US FDA dietary supplement specifications, EU novel food criteria, and regulatory limits on heavy metals, pesticide residues (specifically matching USP <561> parameters), and microbiological assays.
For customers in the European Union and North America, we provide exhaustive technical packages. This includes Allergen Statements, GMO-free certifications, BSE/TSE statements, and detailed flow charts of our manufacturing process. We minimize clearance delays at customs, ensuring your manufacturing line operates smoothly and on schedule.
Essential technical questions answered by the Andy Biotech scientific team.
Complete botanical and functional nutritional ingredients catalog direct from our manufacturing facility.
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