A Comprehensive Industry White Paper on extraction technology, molecular profile optimization, and global supply chain integrations.
Standardized to high concentrations of Rebaudioside A, Rebaudioside M, and Rebaudioside D. Using HPLC validation to ensure consistent flavor profile and zero off-taste notes in sensitive applications.
Leveraging closed-loop water-based extraction and membrane separation, eliminating chemical solvents. Supporting sustainable environmental practices and strict green chemistry standards.
Providing clean calorie reduction without raising insulin levels. The preferred natural sweetening ingredient for diabetic-friendly formulations and modern clean-label keto diets.
The evolutionary trajectory of stevia leaf extraction technology, from simple glycosides to tailored enzymatic optimization.
Historically, the stevia industry relied heavily on Stevioside and Rebaudioside A (Reb A). While abundant, Reb A exhibits a noticeable bitter aftertaste and lingering metallic notes at high concentration levels. To combat this limitation, Andy Biotech's engineering team has pioneered extraction processes focused on minor glycosides: Rebaudioside D (Reb D) and Rebaudioside M (Reb M).
Reb M possesses a sweetness profile closest to sucrose, with virtually zero bitter aftertaste. By combining traditional cultivation selection with advanced physical separation technologies, we have achieved scalable pathways to manufacture high-purity Reb M directly from natural leaves. Our technical roadmap focuses on optimization of physical adsorbent resins and clean crystallisation parameters to isolate these superior glycosides at a fraction of standard historical costs.
In response to the growing global demand for premium steviol glycosides, the future lies in the hybrid model of classic extraction and enzymatic bioconversion. Utilizing food-safe enzymes, we can convert abundant steviol glycosides (like Reb A) into highly valuable, cleaner-tasting molecules (like Reb M) through targeted glucosylation. This bioconversion pathway mimics the natural maturation of the stevia plant, providing a highly scalable, stable, and sustainable supply of sweet compounds without expanding agricultural footprint excessively.
Tailored sweetness solutions engineered to survive extreme food processing conditions and complex formulation matrices.
Sugar Reduction up to 100%: Excellent stability under high-temperature pasteurization (UHT) and acidic pH conditions (e.g., carbonated soft drinks, fruit juices, dairy). Enhances flavor notes while preserving mouthfeel when blended with natural polyols or soluble fibers.
Masking Bitter Actives: Steviol glycosides are vital in masking the astringency of plant proteins, amino acids, and high-dose botanical extracts in protein powders, chewables, and liquid drops. Compatible with clean-label, vegan, and organic dietary formulations.
Safe, Non-Cariogenic Sweetening: Extensively utilized in toothpaste, mouthwash, and lip balms. Possesses excellent thermal and chemical stability, providing sweet notes that do not promote tooth decay or degrade under standard product shelf lives.
Andy Biotech: Your Trusted Partner in Plant Extract Solutions
Andy Biotech is a leading manufacturer and supplier of premium-quality, scientifically-validated plant extracts for the food, beverage, nutraceutical, cosmetic, and pharmaceutical industries. Founded on a commitment to purity, potency, and innovation, we bridge the gap between nature’s potential and your product development goals.
Our core strength lies in our vertically integrated process, which gives us complete control from seed to extract. We partner with a network of certified organic and sustainably managed farms to ensure the integrity of every raw material. Our state-of-the-art extraction facilities employ advanced technologies, including supercritical solvent and water-based methods, to preserve the full spectrum of bioactive compounds without compromising on environmental responsibility.
"Andy was born in a small village close to Hanjiang River in Hanzhong Shaanxi province, China. Thirty years ago, when she was still a little child, she caught a cold, but the medical services were not available unless the family crossed over high mountains to find a hospital. Thus, Andy's grandfather first used Echinacea leaves soaked in water for her treatment, then he dug Echinacea root and shredded into pulp and squeezed the liquid for Andy to drink one spoon every two hours. Andy recovered after this treatment."
As a child, Andy watched his grandfather harness the healing power of plants in his humble garden. His ancient herbal remedies were not just treatments; they were magic. That early wonder blossomed into a profound passion for plant extracts and a deep respect for nature’s wisdom. From that time on, little Andy swore that he would help to spread all herbs all over the world to give benefit to more people.
This personal journey is the heart of Andy Biotech. It’s why Andy Biotech are dedicated to researching and delivering the purest, most effective botanical solutions for modern wellness. Andy’s lifelong vow is to honor that tradition by innovating for a healthier future, empowering lives through the timeless power of plants.
Combining ecological abundance of the Qinling Mountains with state-of-the-art smart manufacturing.
Our primary manufacturing units are situated in Shaanxi Province, adjacent to the Qinling Mountains—often referred to as the natural biological treasure trove of Asia. This geographical placement grants us direct, stable access to rich, pristine botanical resources. Through strategic local farming partnerships, we maintain strict oversight over soil quality, pesticide controls, and heavy metal limits from the very start of the cultivation cycle.
For Steviol Glycosides, our raw stevia leaves are sourced from certified plantations where we control irrigation and harvest periods to optimize the initial accumulation of high-quality glycosides like Reb A, Reb D, and Reb M before processing.
Andy Biotech has incorporated Industry 4.0 standards in our extraction facilities. Our continuous, automated countercurrent extraction systems ensure optimal yields with minimal human intervention, reducing the risk of batch-to-batch contamination. Every critical parameter, including extraction temperature, flow rate, pressure, and solvent ratio, is logged digitally in real-time, feeding our quality management software for full traceability.
A non-negotiable dedication to purity, analytical transparency, and global compliance.
01. Quality and safety are non-negotiable. Every batch undergoes rigorous testing in our in-house laboratories, equipped with HPLC, GC-MS, and other advanced analytical instruments. We guarantee compliance with stringent international standards, including ISO, NSF, cGMP, and related certifications. Our commitment to transparency means you receive comprehensive Certificates of Analysis (CoA) for every product, ensuring traceability and peace of mind.
02. It’s one thing to just meet the regulations when providing ingredients, but when an ingredient supplier exceeds those standards and imposes even higher ones in its products, that is a sign of a company that cares. Andy Biotech takes extra steps to ensure that our independent third-party laboratory-tested ingredients you want meet our standards as well as your own.
03. Our extensive portfolio features a wide range of standardized extracts, ratio extracts, and custom blends tailored to specific formulations. Whether you need Echinacea for immune support, Turmeric with high curcuminoid content, or innovative botanical blends for skincare, our technical team works closely with you to deliver exactly what your product requires. Andy Biotech provides high quality Ginkgo Biloba Extract, Lycopene Tomato Extract, Lutein Marigold Extract, Aloe Vera Gel Freeze Dried powder, Aloe Vera Extract, and other natural ingredients.
Proudly matching global food safety benchmarks with recognized industry credentials.
Mitigating cross-border risks through robust compliance frameworks and local warehouse solutions.
Full alignment with FDA GRAS (Generally Recognized as Safe), EFSA (European Food Safety Authority) standards, and JECFA (Joint FAO/WHO Expert Committee on Food Additives). We guarantee our steviol extracts meet global regulatory requirements for immediate import.
Our processing units are certified with USDA Organic, EU Organic, Kosher, Halal, ISO22000, and FSSC22000. Comprehensive allergen lists, GMO-free statements, and chemical-free processing declarations are provided with every contract.
We leverage international regional distribution hubs to guarantee short delivery times. DDP (Delivered Duty Paid) options and structured supply forecasts assist our enterprise buyers in mitigating supply chain disruptions.
Addressing the critical parameters of high-volume ingredients procurement for mid to large scale manufacturers.
We supply powder in mesh sizes ranging from standard 80 mesh up to 200 mesh superfine powder, and even granular steviol glycosides to reduce dust dispersion during large-scale industrial compounding.
For large food groups wishing to swap out sucrose directly, we build custom sweetening systems. Blend compounds such as Stevia + Erythritol, Stevia + Monk Fruit, or Stevia + Allulose, matching exact sweetness target multipliers (e.g., 1x, 2x, 10x sweetness equivalents).
To hedge against raw material price volatility, Andy Biotech offers annual contract locking. This guarantees a stable price index throughout the fiscal year, ensuring predictability for procurement and finance departments.
Providing direct answers to technical and commercial questions raised by research scientists and procurement managers.
Andy Biotech
