High-purity botanical raw materials meticulously manufactured to meet international nutraceutical and pharmaceutical standards.
CAS 37220-17-0 designates Konjac Glucomannan (KGM), a high molecular weight polysaccharide derived from the corm of the Konjac plant (Amorphophallus konjac). Structurally, it consists of D-mannose and D-glucose monomers linked via β-1,4-glycosidic bonds at a molar ratio of roughly 1.6:1. Regular acetyl groups are distributed along the polymer backbone, which contributes significantly to its solubility and remarkable gel-forming properties.
As a water-soluble dietary fiber, Konjac Glucomannan boasts the highest viscosity of any known natural dietary fiber, reaching values up to 36,000 mPa.s when hydrated at concentrations as low as 1%. This extreme rheological behavior makes it a premier agent for thickening, stabilizing, emulsifying, and texture modifying across various industries, including food processing, pharmaceutical formulation, cosmetic production, and industrial biochemistry.
For enterprise-level procurers sourcing CAS 37220-17-0, regulatory alignment is the cornerstone of operational stability. Global supply chains mandate strict adherence to regional food additive codes, pharmacopeia standards, and chemical safety guidelines.
FDA GRAS (Generally Recognized as Safe) designation. Glucomannan is classified under dietary fiber requirements, needing robust documentation on botanical origin and heavy metal analysis (Lead < 0.5 ppm, Arsenic < 1.0 ppm).
Approved under food additive code E425 (E425i for Konjac Gum, E425ii for Konjac Glucomannan). Subject to European Food Safety Authority (EFSA) exposure assessments and strict maximum limits regarding sulfur dioxide levels.
Compliant with Ministry of Health, Labour and Welfare (MHLW) specifications in Japan. Demands high microbiological clearance (Total Plate Count < 1000 CFU/g, absence of E. coli and Salmonella).
To assist global enterprises in navigating these complex compliance landscapes, Andy Biotech offers end-to-end localized support. This includes customized packaging to prevent moisture absorption, dedicated customs clearance dossiers, and third-party validation (SGS/Eurofins) for specific chemical impurities, pesticide residues, and PAHs (polycyclic aromatic hydrocarbons).
China represents the global epicenter for the cultivation, processing, and export of CAS 37220-17-0. The geographical conditions of central and southwestern China—characterized by rich, well-drained volcanic soils and specific humidity profiles—provide the optimal environment for cultivating high-yield Konjac varieties.
By leveraging Chinese manufacturing advantages, Andy Biotech offers key supply chain benefits:
Andy Biotech: Your Trusted Partner in Plant Extract Solutions
Andy Biotech is a leading manufacturer and supplier of premium-quality, scientifically-validated plant extracts for the food, beverage, nutraceutical, cosmetic, and pharmaceutical industries. Founded on a commitment to purity, potency, and innovation, we bridge the gap between nature’s potential and your product development goals.
Our core strength lies in our vertically integrated process, which gives us complete control from seed to extract. We partner with a network of certified organic and sustainably managed farms to ensure the integrity of every raw material. Our state-of-the-art extraction facilities employ advanced technologies, including supercritical solvent and water-based methods, to preserve the full spectrum of bioactive compounds without compromising on environmental responsibility.
We apply stringent testing methodologies to every botanical extract and custom blend.
Quality and safety are non-negotiable. Every batch undergoes rigorous testing in our in-house laboratories, equipped with HPLC, GC-MS, and other advanced analytical instruments. We guarantee compliance with stringent international standards, including ISO, NSF, cGMP, and related certifications. Our commitment to transparency means you receive comprehensive Certificates of Analysis (CoA) for every product, ensuring traceability and peace of mind.
It’s one thing to just meet the regulations when providing ingredients, but when an ingredient supplier exceeds those standards and imposes even higher ones in its products that is a sign of a company who cares. Andy Biotech takes extra steps to ensure that our independent third-party laboratory-tested ingredients you want meet our standards as well as your own.
Our extensive portfolio features a wide range of standardized extract, ratio extract, and custom blends tailored to specific formulations. Whether you need Echinacea for immune support, Turmeric with high curcuminoid content, or innovative botanical blends for skincare, our technical team works closely with you to deliver exactly what your product requires. Andy Biotech provide high quality Ginkgo Biloba Extract, Lycopene Tomato Extract, Lutein Marigold Extract, Aloe Vera Gel Freeze Dried powder Aloe Vera Extract and other natural ingredients to food, health and nutraceutical industries.
The heritage of natural healing driving modern scientific excellence.
Andy was born in a small village close to Hanjiang River in Hanzhong Shaanxi province, China. Thirty years ago, when she was still a little child, she caught a cold, but the medical services were not available unless the family crossed over high mountains to find a hospital. Thus, Andy's grandfather first used Echinacea leaves soaked in water for her treatment, then he dug Echinacea root and shredded into pulp and squeezed the liquid for Andy to drink one spoon every two hours. Andy recovered after this treatment.
As a child, Andy watched his grandfather harness the healing power of plants in his humble garden. His ancient herbal remedies were not just treatments; they were magic. That early wonder blossomed into a profound passion for plant extracts and a deep respect for nature’s wisdom. From that time on, little Andy swore that he would help to spread all herbs all over the world to give benefit to more people.
This personal journey is the heart of Andy Biotech. It’s why Andy Biotech are dedicated to researching and delivering the purest, most effective botanical solutions for modern wellness. Andy’s lifelong vow is to honor that tradition by innovating for a healthier future, empowering lives through the timeless power of plants.
Globally recognized certifications confirming our operational standards.
The global market demand for CAS 37220-17-0 is experiencing a paradigm shift driven by clean label requirements and the meteoric rise of plant-based foods. In previous decades, synthetic gums or animal-derived gelatin dominated the marketplace. Today, the focus is squarely on natural hydrocolloids.
Key industry trends include:
Understanding how to implement Konjac Glucomannan in specific commercial matrices is key to optimizing functional output:
To replicate the bite and chew resistance of animal fat in plant-based patties or sausages, formulators utilize a thermoirreversible Konjac gel. This is achieved by dissolving CAS 37220-17-0 in water and adding a mild alkali (such as calcium hydroxide) under shear. The resulting gel maintains structural integrity under boiling, baking, or frying conditions.
In dairy alternatives (e.g., oat milk, almond milk), low levels of glucomannan (0.02%–0.05%) prevent phase separation and particle sedimentation without introducing excess viscosity, maintaining a smooth, natural pouring texture.
For skin creams and serums, glucomannan acts as a natural film-forming agent. It deposits a micro-thin, breathable moisture barrier on the stratum corneum, locking in hydration while providing a non-sticky, velvet-like application feel.
Technical and regulatory answers regarding CAS 37220-17-0 procurement.
Explore our extended portfolio of premium natural ingredients for diverse industrial formulations.
Andy Biotech
