CAS 77-52-1, pharmacologically known as Ursolic Acid, is a naturally occurring pentacyclic triterpenoid compound found abundantly in plant cuticles, specifically in rosemary (Rosmarinus officinalis), loquat leaves (Eriobotrya japonica), and apple peels. Known for its distinct hydrophobic crystal structure, Ursolic Acid has transitioned from a niche botanical analyte to a major active pharmaceutical ingredient (API) and functional cosmetics component. Modern industrial interest is fueled by its exceptional anti-inflammatory, anti-proliferative, muscle-sparing (anti-sarcopenic), and collagen-protective biological activities.
From a chemical standpoint, Ursolic Acid (3β-hydroxy-urs-12-en-28-oic acid) poses challenges regarding solubility and human absorption due to its highly lipophilic nature. Leading global chemical suppliers and researchers are focusing heavily on modifying its delivery matrices. Techniques such as liposomal encapsulation, self-emulsifying drug delivery systems (SEDDS), and micronization have surfaced to dramatically enhance bioavailability in vivo. As an exporter committed to technological innovation, Andy Biotech coordinates with top-tier universities to standardize particle sizing, offering micronized CAS 77-52-1 powders tailored for enhanced dissolution profiles in functional foods and clinical cosmetics.
C30H48O3
10% to 98% HPLC
285°C to 288°C
The global demand for CAS 77-52-1 has experienced double-digit compound annual growth rates (CAGR). In the North American market, sports nutrition manufacturers utilize high-purity Ursolic Acid to target the skeletal muscle hypertrophy pathway, where the compound upregulates insulin-like growth factor-1 (IGF-1) signaling. In Europe, the cosmetics industry integrates it as a premium anti-aging agent due to its ability to inhibit matrix metalloproteinase-1 (MMP-1), protecting dermal collagen from degradation. Procurement executives in multinational firms place emphasis on trace pesticide limits, residual solvent profiles (preferring green ethanol over toxic chlorinated solvents), and supply chain continuity.
Andy Biotech: Your Trusted Partner in Plant Extract Solutions
Andy Biotech is a leading manufacturer and supplier of premium-quality, scientifically-validated plant extracts for the food, beverage, nutraceutical, cosmetic, and pharmaceutical industries. Founded on a commitment to purity, potency, and innovation, we bridge the gap between nature’s potential and your product development goals.
Our core strength lies in our vertically integrated process, which gives us complete control from seed to extract. We partner with a network of certified organic and sustainably managed farms to ensure the integrity of every raw material. Our state-of-the-art extraction facilities employ advanced technologies, including supercritical solvent and water-based methods, to preserve the full spectrum of bioactive compounds without compromising on environmental responsibility.
The production of plant metabolites like CAS 77-52-1 requires highly efficient supply lines and state-of-the-art separation technologies. Located in Shaanxi Province—the absolute epicenter of the Chinese botanical extraction industry—Andy Biotech benefits from immediate proximity to key raw materials. The local ecosystem features advanced industrial clustering, providing access to highly specialized equipment, high-throughput chromatographic columns, and a workforce trained in chemical refinement.
By combining vertical raw material integration (directly sourcing loquat leaves from massive domestic agricultural partnerships) with automated continuous-countercurrent extraction lines, we achieve significant economies of scale. This allows us to mitigate price volatility, offering global buyers competitive pricing, rapid turnaround times, and stable supply consistency regardless of seasonal fluctuations.
How we optimize the industrial extraction of Ursolic Acid:
Quality and safety are non-negotiable. Every batch undergoes rigorous testing in our in-house laboratories, equipped with HPLC, GC-MS, and other advanced analytical instruments. We guarantee compliance with stringent international standards, including ISO, NSF, cGMP, and related certifications. Our commitment to transparency means you receive comprehensive Certificates of Analysis (CoA) for every product, ensuring traceability and peace of mind.
It’s one thing to just meet the regulations when providing ingredients, but when an ingredient supplier exceeds those standards and imposes even higher ones in its products that is a sign of a company who cares. Andy Biotech takes extra steps to ensure that our independent third-party laboratory-tested ingredients you want meet our standards as well as your own.
Our extensive portfolio features a wide range of standardized extract, ratio extract, and custom blends tailored to specific formulations. Whether you need Echinacea for immune support, Turmeric with high curcuminoid content, or innovative botanical blends for skincare, our technical team works closely with you to deliver exactly what your product requires. Andy Biotech provide high quality Ginkgo Biloba Extract, Lycopene Tomato Extract, Lutein Marigold Extract, Aloe Vera Gel Freeze Dried powder Aloe Vera Extract and other natural ingredients to food, health and nutraceutical industries.
Andy was born in a small village close to Hanjiang River in Hanzhong Shaanxi province, China. Thirty years ago, when she was still a little child, she caught a cold, but the medical services were not available unless the family crossed over high mountains to find a hospital. Thus, Andy's grandfather first used Echinacea leaves soaked in water for her treatment, then he dug Echinacea root and shredded into pulp and squeezed the liquid for Andy to drink one spoon every two hours. Andy recovered after this treatment.
As a child, Andy watched his grandfather harness the healing power of plants in his humble garden. His ancient herbal remedies were not just treatments; they were magic. That early wonder blossomed into a profound passion for plant extracts and a deep respect for nature’s wisdom. From that time on, little Andy swore that he would help to spread all herbs all over the world to give benefit to more people.
This personal journey is the heart of Andy Biotech. It’s why Andy Biotech are dedicated to researching and delivering the purest, most effective botanical solutions for modern wellness. Andy’s lifelong vow is to honor that tradition by innovating for a healthier future, empowering lives through the timeless power of plants.
Andy Biotech
