China Rosemary Leaf Extract CAS 77-52-1 Manufacturers & Factories

State-of-the-Art Plant Extraction & Sustainable Industrial Supply of Ursolic Acid & Carnosic Acid

Industrial Monograph

Rosemary Leaf Extract (CAS 77-52-1) & Global Market Landscape

Rosemary Leaf Extract, primarily standardized to Ursolic Acid (represented by CAS number 77-52-1), represents one of the most critical naturally derived triterpenoids used in modern functional foods, pharmaceuticals, and cosmeceuticals. As consumer dynamics shift decisively away from synthetic preservatives (such as BHA, BHT, and TBHQ) toward plant-derived "clean label" formulations, Rosemary Leaf Extract has surged to the forefront of the global antioxidant and active ingredient markets.

CAS 77-52-1 (Ursolic Acid) is a pentacyclic triterpenoid carboxylic acid displaying remarkable pharmacological profiles, including heavy antioxidant, anti-inflammatory, antimicrobial, and cell-modulating properties. The global commercialization of Rosemary Leaf Extract spans multiple standardization profiles—notably water-soluble Rosmarinic Acid, oil-soluble Carnosic Acid, and highly purified Ursolic Acid crystal powders. China has evolved as the preeminent global manufacturing hub, driving key breakthroughs in green chemistry extraction protocols and robust industrial supply lines.

Key Insight for Purchasing Directors: By selecting a vertically integrated manufacturer from China, global formulation brands guarantee batch-to-batch consistency, pesticide-free botanical raw materials, and long-term price stability.
Andy Biotech State-of-the-art manufacturing

Technical Roadmap & Extraction Methodologies

Achieving structural stability and maximizing the bioavailability of triterpenes and polyphenols requires sophisticated, eco-responsible processing technology.

Supercritical CO₂ Extraction

Designed to extract oil-soluble components like Carnosic Acid without the use of harsh organic solvents. This low-temperature, high-pressure process ensures a zero-solvent-residue profile, perfect for premium organic-certified formulations.

Column Chromatography & Purity Gradients

For high-purity CAS 77-52-1 (Ursolic Acid) ranging from 50% to 98% white crystalline powder, column isolation is employed. Precise temperature control and solvent crystallization preserve molecular integrity and structure.

Advanced Standardization

Every batch of Rosemary Leaf Extract is standardized through high-performance liquid chromatography (HPLC) ensuring chemical profile homogeneity and reliable biological activity in every production run.

Active Compound / Marker CAS Registry Number Common Standardized Strengths Primary Industrial Applications
Ursolic Acid CAS 77-52-1 10%, 25%, 50%, 90%, 98% HPLC Cosmeceuticals, cellular health supplements, anti-aging creams.
Carnosic Acid CAS 3650-09-7 5%, 10%, 20%, 60%, 95% HPLC (Oil/Powder) Natural food preservative, lipid stability, pet food formulation.
Rosmarinic Acid CAS 20283-92-5 2.5%, 5%, 10%, 15%, 20% HPLC (Water Soluble) Beverage stabilization, functional health drinks, oral care.

Localized Commercial & Industrial Applications

How global industries are integrating China-manufactured CAS 77-52-1 to elevate product performance and satisfy strict clean-label regulatory frameworks.

1. Cosmeceuticals & Skincare

Highly purified Ursolic Acid (CAS 77-52-1) is utilized in topical skincare to inhibit elastase and collagenase, protecting the extracellular matrix. Its anti-inflammatory action makes it highly effective for barrier-repair serums.

2. Clean-Label Food Preservation

Carnosic acid powders act as potent free radical scavengers in frying oils and processed meats. Rosemary extract replaces synthetics like BHT to satisfy USDA/EFSA demands for natural origin statements.

3. Nutraceuticals & Longevity

In dietary supplements, Ursolic Acid is widely studied for its ability to prevent muscle atrophy (sarcopenia) and support metabolic health, finding wide use in longevity and sports nutrition formulations.

4. Premium Animal Nutrition

In pet food, Rosemary extracts prevent oxidation of natural fats. It is a preferred ingredient in export-grade, grain-free dog and cat food kibble due to its safety and stability profiles.

Andy Biotech supply chain quality control
Supply Chain Leadership

China Factory Supply Chain Resilience & Cost-Efficiency

Our vertically integrated raw material sourcing network guarantees that our rosemary crops are cultivated in ideal agricultural zones with full oversight on pesticide residues, heavy metals, and sustainability. Having complete control over cultivation, harvesting, and extraction shields our global partners from market price volatility.

By leveraging advanced automation in our Chinese manufacturing facilities, we deliver high-capacity throughput while keeping our production costs highly competitive. We operate modern logistics hubs with direct channels to major maritime shipping lines and global express couriers, ensuring stable delivery of phytocompounds to your formulation facility.

  • Direct farm-to-factory pipeline ensuring raw material traceability.
  • Annual production capacity exceeding several hundred metric tons.
  • Customizable particle sizes, bulk densities, and water/oil solubilities.

Rigorous Quality Assurance & Compliance Framework

Our dedicated QA/QC testing program ensures every cargo shipment meets the demanding quality specifications of global regulatory bodies.

100%
In-House Analytical Verification

Equipped with HPLC, GC-MS, AAS, and microbiology facilities, we trace contaminants, residual solvents, and active values in real-time.

USP/EP
Pharmacopoeia Compliance

Our standardized powders strictly follow United States Pharmacopoeia (USP) and European Pharmacopoeia (EP) analytical methods.

< 10ppm
Heavy Metal Threshold limit

We guarantee highly purified raw materials featuring low levels of Arsenic, Lead, Cadmium, and Mercury.

Andy Biotech Factory Certifications & Quality Standard Endorsements

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About Andy Biotech

Andy Biotech is a leading manufacturer and supplier of premium-quality, scientifically-validated plant extracts for the food, beverage, nutraceutical, cosmetic, and pharmaceutical industries. Founded on a commitment to purity, potency, and innovation, we bridge the gap between nature’s potential and your product development goals.

Our core strength lies in our vertically integrated process, which gives us complete control from seed to extract. We partner with a network of certified organic and sustainably managed farms to ensure the integrity of every raw material. Our state-of-the-art extraction facilities employ advanced technologies, including supercritical solvent and water-based methods, to preserve the full spectrum of bioactive compounds without compromising on environmental responsibility.

It’s one thing to just meet the regulations when providing ingredients, but when an ingredient supplier exceeds those standards and imposes even higher ones in its products, that is a sign of a company who cares. Andy Biotech takes extra steps to ensure that our independent third-party laboratory-tested ingredients meet our standards as well as your own.

Our extensive portfolio features a wide range of standardized extracts, ratio extracts, and custom blends tailored to specific formulations. Whether you need Echinacea for immune support, Turmeric with high curcuminoid content, or innovative botanical blends for skincare, our technical team works closely with you to deliver exactly what your product requires. Andy Biotech provides high quality Ginkgo Biloba Extract, Lycopene Tomato Extract, Lutein Marigold Extract, Aloe Vera Gel Freeze Dried powder, Aloe Vera Extract, and other natural ingredients to the food, health, and nutraceutical industries.

Andy Biotech laboratories and equipment
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Our Heritage

Our Story

Andy was born in a small village close to Hanjiang River in Hanzhong Shaanxi province, China. Thirty years ago, when she was still a little child, she caught a cold, but medical services were not available unless the family crossed over high mountains to find a hospital. Thus, Andy's grandfather first used Echinacea leaves soaked in water for her treatment, then he dug Echinacea root and shredded it into pulp, squeezing the liquid for Andy to drink one spoon every two hours. Andy recovered after this treatment.

As a child, Andy watched her grandfather harness the healing power of plants in his humble garden. His ancient herbal remedies were not just treatments; they were magic. That early wonder blossomed into a profound passion for plant extracts and a deep respect for nature’s wisdom. From that time on, little Andy swore that she would help to spread herbs all over the world to benefit more people.

This personal journey is the heart of Andy Biotech. It’s why Andy Biotech is dedicated to researching and delivering the purest, most effective botanical solutions for modern wellness. Andy’s lifelong vow is to honor that tradition by innovating for a healthier future, empowering lives through the timeless power of plants.

Industrial Q&A & Technical FAQ

Comprehensive technical answers to critical formulation questions on Rosemary Leaf Extract & CAS 77-52-1.

What is the specific functionality of CAS 77-52-1 (Ursolic Acid) compared to other components in Rosemary?

CAS 77-52-1 refers to Ursolic Acid, which is a triterpenoid. While Carnosic Acid and Rosmarinic Acid primarily act as rapid radical scavengers preventing lipid peroxidation in oils and beverages, Ursolic Acid targets cellular pathways, supporting skin health, tissue integrity, and healthy muscle metabolism. It is widely used in anti-aging skin formulations and functional health supplements.

How does your factory ensure the absence of organic solvent residues in your extracts?

We use advanced extraction systems including Supercritical Fluid Extraction (SFE) with CO₂. Since CO₂ returns to its gaseous state at normal atmospheric pressure, it evaporates completely, leaving behind zero organic solvent residues. This is the optimal standard for premium green labels.

What certifications are available with each shipment?

Every delivery includes a batch-specific Certificate of Analysis (CoA) containing our testing values for heavy metals, pesticide profiles, microbiological thresholds, and HPLC active assays. Our plant facilities operate under certifications including ISO, cGMP, NSF, Kosher, and Halal.

How does Rosemary Leaf Extract compare to synthetic alternatives?

Rosemary Leaf Extract contains natural antioxidants that provide high thermal stability, keeping active oils stable under cooking conditions without presenting the potential safety challenges linked to synthetic compounds like BHA or BHT.