Best Stable Supply Citrus Aurantium Extract 98% Neohesperidin with CAS 13241-33-3 for Supplement Manufacturer, Supplier

Neohesperidin is a valuable citrus flavonoid. Its primary industrial role is as the raw material for the super-high-potency sweetener NHDC. Beyond its industrial use, it is a bioactive compound with promising antioxidant, anti-inflammatory, and vascular-protective properties, making it a subject of interest for health and pharmaceutical research.

Product Description

Introduction of Neohesperidin

Neohesperidin is a natural flavanone glycoside extracted and purified from citrus peels through advanced separation and crystallization technology.

It possesses notable properties including antioxidant, anti-inflammatory, flavor modifying and bitterness masking effects.

Purity: 98% (HPLC)
CAS No.: 13241-33-3
Molecular Formula: C₂₈H₃₄O₁₅
Molecular Weight: 610.56
Source: Bitter orange peel, citrus fruits
Appearance: White to off-white crystalline powder
Solubility: Slightly soluble in cold water, soluble in hot water, methanol, and ethanol
Neohesperidin, CAS 13241-33-3

Function of Neohesperidin

Neohesperidin, a citrus-derived flavanone glycoside, exerts potent free radical scavenging and anti-inflammatory effects by inhibiting inflammatory factors and modulating stress-related pathways.

It protects cardiovascular health by enhancing capillary toughness, improving microcirculation, and maintaining normal vascular permeability.

Additionally, it regulates intestinal flora, supports liver function by reducing fat accumulation and hepatocyte damage, and serves as a key precursor for NHDC—a high-intensity low-calorie sweetener 1,500–2,000 times sweeter than sucrose.

Its antioxidant and anti-aging properties also make it valuable for skin care, while it aids in balancing blood lipids and alleviating intestinal inflammation.

Neohesperidin, CAS 13241-33-3

Application Area of Neohesperidin

Food Industry

  • Raw material for synthesizing neohesperidin dihydrochalcone (NHDC) a high-intensity sweetener.
  • Used as a flavor enhancer, bitterness masking agent, and preservative in beverages, candy, baked goods, and low-sugar foods.

Pharmaceuticals & Health

  • Cardiovascular health supplements to improve capillary fragility and microcirculation.
  • Antioxidant and anti-inflammatory ingredients for liver protection and metabolic regulation.
  • Used in oral and gastrointestinal healthcare formulations.

Cosmetics & Skin Care

  • Antioxidant, anti-aging, and soothing components in creams, serums, and lotions.
  • Inhibits melanin production, brightens skin, and relieves redness and sensitivity.

Daily Chemical & Feed

  • Added in toothpaste, mouthwash, and chewing gum to enhance flavor and mask bitterness.
  • Used as a natural antioxidant and growth promoter to improve animal intestinal health and immunity.

Product Specification of Neohesperidin

Neohesperidin, CAS 13241-33-3 Technical Data Sheet
Sense Index
Appearance Light yellow to off-white powder
Odor & Taste Characteristic
Physical-chemical Index
Neohesperidin 98% Min
Loss on drying 5% Max
Ash 5% Max
Particle Size 98% pass 80 mesh
Heavy metals 10ppm Max
Lead 2ppm Max
Arsenic 2ppm Max
Mercury 0.1ppm Max
Cadmium 1ppm Max
Hygienic Index
Total plate count 1,000cfu/g Max
Mold & yeast 100cfu/g Max
Enterobacteriae 10cfu/g Max
E.Coli Absent in 10g
Salmonella Absent in 25g

Frequently Asked Questions (FAQ)

QWhat is the primary botanical source of Neohesperidin?

Neohesperidin is mainly extracted and purified from bitter orange peel and other citrus fruits using advanced separation and crystallization technology.

QHow pure is this Neohesperidin powder?

Our Neohesperidin powder has a minimum purity of 98% when measured by High-Performance Liquid Chromatography (HPLC) standards.

QWhat are the key benefits of Neohesperidin in cosmetics?

In cosmetics, it acts as an antioxidant, anti-aging, and soothing agent. It helps inhibit melanin production, brightens skin tone, and relieves redness or skin sensitivity.

QHow does Neohesperidin function in the food industry?

It is widely used as a flavor enhancer, bitterness masking agent, and preservative in beverages, candies, and baked goods. It also serves as the essential precursor for synthesizing the sweetener NHDC.

QWhat are the storage guidelines and shelf life for this product?

It has a shelf life of 24 months. For optimal quality, it must be stored in its original packaging, protected from light, and kept at temperatures between 10℃ and 25℃.

QIs the Neohesperidin powder GMO-free?

Yes, the product comes with a statement guaranteeing that it is both Non-Irradiated and Non-GMO.

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