Explore our standardized high-potency active components validated by state-of-the-art laboratory testing.
CAS 537-42-8, chemically designated as trans-3,5-dimethoxy-4'-hydroxystilbene and widely known as Pterostilbene, represents one of the most commercially significant polyphenols in the global active pharmaceutical ingredient (API) and high-end nutraceutical markets. As a natural dimethylated analog of resveratrol, Pterostilbene possesses structural attributes that dramatically improve its pharmacokinetics, making it a highly sought-after molecule for longevity, anti-inflammatory, cognitive, and cardiovascular health formulations.
The fundamental difference between Resveratrol and Pterostilbene (CAS 537-42-8) lies in their molecular structure. Pterostilbene replaces two hydroxyl groups with methoxy groups. This small structural modification increases the lipophilicity of the molecule, accelerating cellular uptake and drastically extending its physiological half-life. While natural resveratrol exhibits a low oral bioavailability of approximately 20%, Pterostilbene achieves an impressive bioavailability of nearly 80%. This pharmacokinetic superiority translates to lower dose requirements and enhanced formulation performance for global brands.
| Property Parameter | Technical Specification Value |
|---|---|
| Chemical Name | trans-3,5-Dimethoxy-4'-hydroxystilbene; Pterostilbene |
| CAS Registry Number | 537-42-8 |
| Molecular Formula | C16H16O3 |
| Molecular Weight | 256.3 g/mol |
| Appearance | White or off-white crystalline powder |
| Assay Purity (HPLC) | ≥ 98.0% / ≥ 99.0% (Pharma Grade / Dietary Grade) |
| Solubility | Soluble in ethanol, DMSO, and dimethyl formamide; poorly soluble in water |
| Storage Conditions | Stored in a cool, dry, dark area in original air-tight packaging |
Why leading global enterprises partner with Chinese manufacturers for high-volume botanical intermediates.
By controlling the process from botanical cultivation networks in local provinces to advanced purification loops, our factory ensures constant raw material supply, bypassing external market volatility.
We utilize low-temperature extraction, supercritical carbon dioxide, and green solvent synthesis protocols that maximize yield while complying with strict international ecological guidelines.
Our large-scale production facilities drastically reduce unit costs, sharing economic benefits with foreign distributors, compounders, and pharmaceutical developers looking to scale.
China's Shaanxi province, and particularly the botanical extraction clusters in Hanzhong, have evolved into global hubs for phytochemical synthesis. Benefiting from regional transport networks, specialized research universities, and comprehensive supply chain infrastructure, we can ship high-tonnage orders of CAS 537-42-8 rapidly to Europe, North America, and Southeast Asia. This enables our enterprise clients to maintain lean inventory systems while mitigating import disruption risks.
Pterostilbene is widely integrated into premium consumer categories worldwide.
As an epigenetic regulator, Pterostilbene acts on sirtuin pathways, specifically SIRT1, similar to Resveratrol but with higher bioavailability. It is heavily utilized in anti-aging supplement formulas, often paired with NMN (Nicotinamide Mononucleotide) or Coenzyme Q10.
Target Markets: North America, EU, JapanDue to its high lipophilicity, CAS 537-42-8 crosses the blood-brain barrier effectively. Researchers and brands include Pterostilbene in memory boosters, concentration capsules, and stress-response formulations to support neural resilience.
Target Markets: global health-conscious demographicsTopical application of Pterostilbene protects skin cells against UV-induced oxidative stress and assists in regulating melanin production. Formulation chemists add cosmetic-grade CAS 537-42-8 to anti-wrinkle serums and skin brightening lotions.
Target Markets: Korea, EU, Asia-PacificBy activating AMPK and regulating lipid pathways, Pterostilbene helps maintain healthy glucose and blood pressure levels. It is a vital raw ingredient in metabolic health pills and cardiovascular defense blends.
Target Markets: Global pharmaceutical & nutraceutical channelsAndy Biotech: Your Trusted Partner in Plant Extract Solutions
A deep dive into our testing procedures, compliance, and custom biological blends.
Quality and safety are non-negotiable. Every batch undergoes rigorous testing in our in-house laboratories, equipped with HPLC, GC-MS, and other advanced analytical instruments. We guarantee compliance with stringent international standards, including ISO, NSF, cGMP, and related certifications. Our commitment to transparency means you receive comprehensive Certificates of Analysis (CoA) for every product, ensuring traceability and peace of mind.
It’s one thing to just meet the regulations when providing ingredients, but when an ingredient supplier exceeds those standards and imposes even higher ones in its products that is a sign of a company who cares. Andy Biotech takes extra steps to ensure that our independent third-party laboratory-tested ingredients you want meet our standards as well as your own.
Our extensive portfolio features a wide range of standardized extract, ratio extract, and custom blends tailored to specific formulations. Whether you need Echinacea for immune support, Turmeric with high curcuminoid content, or innovative botanical blends for skincare, our technical team works closely with you to deliver exactly what your product requires. Andy Biotech provide high quality Ginkgo Biloba Extract, Lycopene Tomato Extract, Lutein Marigold Extract, Aloe Vera Gel Freeze Dried powder Aloe Vera Extract and other natural ingredients to food, health and nutraceutical industries.
Adapting to evolving global standards to ensure seamless distribution.
Securing supply lines requires navigating regulatory frameworks like US FDA GRAS (Generally Recognized as Safe), European Food Safety Authority (EFSA) Novel Food applications, and local health authorities. Our regulatory department compiles dossiers on chemical stability, heavy metal parameters (lead, cadmium, arsenic, mercury under 1ppm), and microbial counts to ensure compliance in Europe, the Americas, and Australasia.
Market data indicates a compound annual growth rate (CAGR) of over 7.2% for Pterostilbene (CAS 537-42-8) globally, driven by a growing middle-aged demographic seeking anti-aging options. Consumers are demanding science-backed active ingredients over simple botanical powders. Manufacturers who provide third-party chromatographic validation are capturing a larger share of this high-value market.
Validated safety systems across international production boundaries.
Technical and logistical insights for global procurement agents and distributors.
A further selection of our manufacturing portfolio, supporting clean labels and traceable sourcing.
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